Dendritic cell-targeting DNA-based mucosal adjuvants for the development of mucosal vaccines
نویسندگان
چکیده
منابع مشابه
Choice and Design of Adjuvants for Parenteral and Mucosal Vaccines
The existence of pathogens that escape recognition by specific vaccines, the need to improve existing vaccines and the increased availability of therapeutic (non-infectious disease) vaccines necessitate the rational development of novel vaccine concepts based on the induction of protective cell-mediated immune responses. For naive T-cell activation, several signals resulting from innate and ada...
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Vaccination is the most successful immunological practice that improves the quality of human life and health. Vaccine materials include antigens of pathogens and adjuvants potentiating the effectiveness of vaccination. Vaccines are categorized using various criteria, including the vaccination material used and the method of administration. Traditionally, vaccines have been injected via needles....
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Vaccine adjuvants induce innate immune responses and the addition of adjuvants to the vaccine helps to induce protective immunity in the host. Vaccines utilizing live attenuated or killed whole pathogens usually contain endogenous adjuvants, such as bacterial cell wall products and their genomic nucleic acids, which act as pathogen-associated molecular patterns and are sufficient to induce adap...
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ژورنال
عنوان ژورنال: Expert Review of Vaccines
سال: 2009
ISSN: 1476-0584,1744-8395
DOI: 10.1586/erv.09.80